The main aim of this course is to provide the fundamentals of bioprocess design.

  • Course Title: Principles of Bioprocess Design
  • Course Type: Lecture
  • Course No: 211400401
  • Credits/Weeks: 2/17
  • Semester: Fall
  • Group Presenting: Biotechnology



Part I: Introduction to process design

Part II: Conceptualization and Analysis of Bioprocess

Part III: Synthesis and Optimization

Part IV: Economic Analysis of Bioprocess


G., Towler, K.S., Ray “Chemical engineering design: principles, practice and economics of plant and process design“, Elsevier, 2012.

Turton, R., R.C., Bailie, W.B., Whiting, J.A., Shaeiwitz, “Analysis, synthesis and design of chemical processes“, Pearson Education, 2008.

W.D., Seider, J.D., Seader, D.R., Lewin, “Product & process design principles: synthesis, analysis and evaluation“, John Wiley & Sons, 2009.

R.G. Harrison, P.W. Todd, S.R. Rudge, D.P. Petrides, “Bioseparations Science and Engineering”, Oxford, 2015.



SuperPro Designer:

Design and Optimization of a Large Scale Biopharmaceutical Facility using Process Simulation and Scheduling Tools

The article

The process


SuperPro Designer & other interesting files

Homework 2) Continuous processes with recycle loops

      A simple fermentation process dealing with baker’s yeast production.

      Part 1     Part 2

Homework 3) Monoclonal Antibody Production

Examination method

Mid. Term Exam 20-40%
Final Exam 30-50%
Project 15-35%
Home works 5%

Teaching Method: Lectures